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罗晓燕
发布时间：2015-06-15   访问次数:18435   作者:

罗晓燕  教授
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电话: 021-64252879
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传真:
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E-mail: xyluo@ecust.edu.cn
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  个人简介
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    女，博士， 先后毕业于武汉工程大学,获工学学士，南京工业大学，获工学硕士学位，华东理工大学获博士学位，博士期间从事有机不对称催化的合成方法学研究。1993-2003年在武汉工程大学化学制药系工作，主要从事制药合成工艺与工程方面的科研教学工作，2003年至今工作于环球360游戏， 主要从事制药工程设计，有机合成方法学、有机小分子参与的不对称催化方面的研究工作。已在国内外主要刊物上发表论文30余篇，申请中国专利1项，先后主持或参与科研项目9项，其中省部级3项。获得上海市教学成果一等奖 2 项（2017 年，排名第一；2013 年，排名第二）、宝钢优秀教师奖。指导学生参加了六届全国大学生制药工程设计竞赛，获得一等奖 4 项。上海市重点课程和虚拟仿真实验教学项目负责人，主持或参与各级教改项目10余项，主编或参编教材 5 本，发表教学论文 10余篇、服务于教学的实用新型专利 1 项、教学软件著作权 5 项。

 

近期主要文章：

1. Na Yang, Fei Wu, Jiabin Gao,Luo Xiaoyan, Weimin Yue，Synthesis of 3-Methyl-2,6-dimethylbicyclo[3.3.1]nonane-exo-2,exo-6-diol, Synth. Commun, 2009, 39（21）, 3934-3939.

2.   Luo Xiaoyan, Zhichao Jin, Pengfei Li, Jiabin Gao, Weimin Yue, Xinmiao Liang, Jinxing Ye, Catalytic Asymmetric Michael Addition of α, β-Unsaturated Aldehydes with Ni(II) Complexes of the Schiff Base of Glycine, Org. Biomol. Chem., 2011, 9 (3), 793-801.

3.  Luo Xiaoyan, Zhiqiang Zhou, Feng Yu, Xin Li, Xinmiao Liang, Jinxing Ye. Asymmetric Vinylogous Michael Reaction of α, β-Unsaturated Aldehyde With γ-Butenolide. Chem.Lett., 2011, 40(5),518-520.

4.  Luo Xiaoyan, Zhiqiang Zhou, Xin Li, Xinmiao Liang and Jinxing Ye organocatalytic phospha-Michael reaction of α,β-unsaturated aldehydes. RSC Adv., 2011, 1, 698-705.

5.  Zhichao Jin, Huicai Huang, Wenjun Li, Luo Xiaoyan, Xinmiao Liang, Jinxing Ye, Enantioselective Organocatalytic Synthesis of Oxazolidine Derivatives through A One-pot Cascade Reaction, Adv. Synth. Catal., 2011, 353, 343-348.

6.  Zhichao Jin, Feng Yu, Xiao Wang, Huicai Huang, Luo Xiaoyan, Xinmiao Liang, Jinxing Ye, A One-pot Asymmetric Organocatalytic Tandem Reaction for the Synthesis of Oxazine Derivatives, Org. Biomol. Chem., 2011, 9, 1809-1816.

7. Li Yi, Cao Li, Luo Xiaoyan, Deng Wei-Ping.Highly Substituted Cyclopentenes Formation via a Stereoselective Tandem CDC Reaction and Cyclization, Chin. J. Chem. 2012,30, 2834-2838.

8. Wang Zheng, Shi Ying, Luo Xiaoyan, Han De-Man , Deng Wei-Ping. Direct synthesis of pyrroles via 1,3-dipolar cycloaddition of azomethine ylides with ynones. New J. Chem., 2013, 37,1742-1745.

9. Wang Zheng, Luo Shuai, Zhang Shoude, Yang Wu-Lin, Liu Yang-Zi, Li Honglin, Luo Xiaoyan , Deng Wei-Ping. Catalytic Asymmetric Construction of Quaternary a-Amino Acid-Containing Pyrrolidines via 1,3-Dipolar Cycloaddition of Azomethine Ylides to a-AminoacrylatesChem. Eur. J., 2013, 19,6739-6745.

10. Wei-Liang Wang, Yu-Lan Feng, Wen-Qiang Gao, Luo Xiaoyan , Wei-Ping Deng. A highly efficient BF3.Et2O-catalysed intramolecular [3+2] cycloaddition for the synthesis of 3,4-dihydrobenzopyrano[3,4-c]pyrazoles, RSC Advances,2013, 3, 1687-1690. 

11. Zheng-Lin Wang, Hong-Liang Li , Li-Shi Ge , Xing-Lan An , Zi-Gang Zhang , Luo Xiaoyan, John S. Fossey, Wei-Ping Deng ,DDQ-Mediated Oxidative Coupling: An Approach to 2,3-Dicyanofuran (Thiophene),J. Org. Chem., 2014, 79 (3), 1156–1165.(Highlights in SYNFACTS2014, 10(4), 0374).

12. Wang Zheng-Lin, An Xing-Lan, Ge Li-Shi, Jing-Hai Jin, Luo Xiaoyan , Deng Wei-Ping. DDQ-mediated oxidation of sp3 C-H bond for the direct synthesis of vicinal tricarbonyl compounds. Tetrahedron2014, 70, 3788-3792.
   
  13.   Li Yi, Cao Li, Luo Xiaoyan, Deng Wei-Ping. The synthesis of 1, 2-diarylindenes   via DDQ-mediated dehydrogenative intramolecular cyclization. Tetrahedron2014, 70, 5974.

14. Ge Li-Shi, Wang Zheng-Lin, An Xing-Lan, Luo Xiaoyan, Deng Wei-Ping ,Direct synthesis of polysubstituted 2-aminothiophenes by Cu(II)-catalyzed addition/oxidative cyclization of alkynoates with thioamides, Org. Biomol. Chem. 2014, 12, 8473-8479.

15. Luo Xiaoyan, Wang Z-L, Jin J-H, An X-L, Shen Z, Deng Wei-Ping, Copper-catalyzed α-aminoxylation of 1,3-dicarbonyl compounds with 2,2,6,6-tetramethylpiperidine-1-oxyl (TEMPO) via an aerobic oxidative sp3 C-H bond activation, Tetrahedron2014, 70, 8226-8230. 

16.Luo Xiaoyan, Li-Shi Ge, Xing-Lan An, Jing-Hai Jin, Yu Wang,Pei-Pei Sun and Wei-Ping Deng. Regioselective Metal-Free One-pot Synthesis of Functionalized 2-Aminothiophene Derivatives. J. Org. Chem. 2015,80, 4611-4617.

17.Hong-Liang Li, Xing-Lan An, Li-Shi Ge, Luo Xiaoyan, Wei-Ping Deng. Catalytic α-Hydroxylation of Ketones under CuBr2 or HBr/DMSO Systems.Tetrahedron2015, 71, 3247-3252.

18. Li Chun-Yan , Yang Wu-Lin ,  Luo Xiaoyan, Wei-Ping Deng.Diastereodivergent Asymmetric Michael Addition of Cyclic Azomethine Ylides to Nitroalkenes: Direct Approach for the Synthesis of 1,7-Diazaspiro[4.4]nonane Diastereoisomers,Chem. Eur. J. 2015, 21, 19048–19057.

19. Li Hong-Liang, Wang Yu, Sun Pei-Pei, Luo Xiaoyan, Shen Zhenlu, Deng Wei-Ping.α,β-Double electrophilic addition of allene-1,3-dicarboxylic esters for the construction of polysubstituted furans via KI/TBHP promoted oxidative annulation.Chem. Eur. J. 2016, 22, 9348-9355.

20. Wang Yu, Jiang Chen-Min, Li Hong-Liang, He Fu-Sheng, Luo Xiaoyan, Deng Wei-Ping.Regioselective Iodine-catalyzed Construction of Polysubstituted Pyrroles from Allenes and Enamines.J. Org. Chem.2016, 81, 8653-8658.

21. Liu Yang-Zi, Shang Shao-Jing, Yang Wu-Lin, Luo Xiaoyan, Deng Wei-Ping.Stereoselective Synthesis of Pyrrolidines Containing a 3‑Fluoro Quaternary Stereocenter via Copper(I)-Catalyzed Asymmetric 1,3-Dipolar Cycloaddition.J. Org. Chem. 2017, 82(20), 11141-11149.

22. Han Teng, Wang Yu, Li Hong-Liang, Luo Xiaoyan, Deng Wei-Ping.Synthesis of Polysubstituted 3-Aminothiophenes from Thioamides and Allenes via Tandem Thio-Michael Addition/Oxidative Annulation and 1,2-Sulfur Migration. J. Org. Chem.2018, 83, 1538-1542.

23. Teng Han,Luo Xiaoyan .Thio-Michael addition of thioamides and allenes for the selective construction of polysubstituted 2-arylthiophenes via TBAI/H2O2 promoted tandem oxidative annulation and 1,2-sulfur migration.Org. Biomol. Chem.2018, 16, 6875-6879.

24. Leng Jiaying, Meng Jiang, Luo Xiaoyan, Deng Wei-Ping. Formal [4 + 1] Cycloaddition Strategy for the Synthesis of Dihydrobenzofurans via Michael Addition of 2-(2-nitrovinyl)-phenols and Malonate Esters (C1 Synthon) and Subsequent Iodine-catalyzed Oxidative Annulation.Tetrahedron 2018, 74, 6993-6999.

25. Jin Jing-Hai, Li Xiang-Yu, Luo Xiaoyan, Deng Wei-Ping. Enantioselective synthesis of indolo[2,3-b]-dihydrothiopyranones via [3+3] cycloaddition of chiral α,β-unsaturated acylammonium salts.Tetrahedron 2018, 74, 6804-6808.

26. Wen Min, Sun Pei-Pei, Luo Xiaoyan, Deng Wei-Ping .Cu(II)-catalyzed one-pot synthesis of fully substituted dihydrothiophenes and thiophenes from thioamides and enynones.Tetrahedron 2018, 74(31), 4168-4173.

27. Wu Shu-Xiao, Gu Bo-Qi, Xu Hui, Zheng Xing, Luo Xiaoyan, Deng Wei-Ping.Organocatalytic Asymmetric Inverse-Electron-Demand Diels-Alder Reaction of Pyrrolidone-Dienes with Enals .Adv. Synth. Catal. 2019, 361(18), 4302-4313.

28. Mao Jia, Zhang Hao, Ding Xiang-Feng, Luo Xiaoyan, Deng Wei-Ping .Synergistic Catalysis for Asymmetric [3 + 2] Cycloadditions of 2-Indolylmethanols with α,β-Unsaturated Aldehydes.J. Org. Chem. 2019, 84(17), 11186-11194.

29. Leng Jiaying, Xu Hui, Meng Jiang, Luo Xiaoyan, Deng Wei-Ping.Transition-metal-free synthesis of polysubstituted pyrrole derivatives via [4+1] annulation of beta-keto acids (C1 synthon) and alpha,beta-unsaturated imines.Tetrahedron 2019, 75, 130709

30. Chao Ye, Wu-Lin Yang, Yufei Zhai, Hua Deng, Luo Xiaoyan, Guoyin Kai， Wei-Ping Deng. Copper(I)-Catalyzed Asymmetric [3 + 3] Annulation Involving Aziridines to Construct Tetrahydro-ß-carbolines. Org. Chem. Front., 2020, 7, 3393-3398.

31. Hua Deng, Tian-Tian Liu, Zheng-Dong Ding, Wu-Lin Yang, Luo Xiaoyan，Wei-Ping Deng.Kinetic resolution of 2H-azirines via Cu(i)-catalyzed asymmetric 1,3-dipolar cycloaddition of azomethine ylides.Org. Chem. Front., 2020,7, 3247-3252.

32. Xu Hui, Han Teng, Luo Xiaoyan, Deng Wei-Ping. The construction of 3-azabicyclo[3.1.0]hexane backbone by the reaction of allenes with allylamines via tandem aza-Michael addition and Copper-mediated oxidative carbanion cyclization. Chin. J. Chem., 2021, 39, 666-670.

33. Yang Wu-Lin, Liu Tian-Tian, Ni Tao, Zhu Bin,  Luo Xiaoyan, Deng Wei-Ping. Iridium-Catalyzed Asymmetric Cascade Allylation/Pictet-Spengler Cyclization Reaction for the Enantioselective Synthesis of 1,3,4-Trisubstituted Tetrahydroisoquinolines.Org. Lett., 2021, 23(7), 2790-2796.

34. Yang Wu-Lin, Wang Yuan-Lin, Li Wen, Gu Bu-Ming, Wang Si-Wen, Luo Xiaoyan, Tian Bo-Xue, Deng Wei-Ping. Diastereo- and Enantioselective Synthesis of Eight-Membered Heterocycles via an Allylation/Ring Expansion Sequence Enabled by Multiple Catalysis. ACS Catal., 2021, 11, 12557-12564.

研究方向
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    有机合成方法学；有机小分子参与的不对称催化；制药工程设计